AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice
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چکیده
منابع مشابه
Gastroprotective and antioxidant potential of Glycyrrhiza glabra on experimentally induced gastric ulcers in albino mice
Ulcer is the lesion that pierces the muscularis mucosa which does not show the tendency to heal. Its etiology mainly includes imbalance between offensive and protective factors in mucosa of stomach such as mucosal barriers, cellular regeneration, acid-pepsin secretion, blood flow and epidermal growth factors (Lima et al., 2006). This imbalance usually happened as consequence of H. pylori infect...
متن کاملGastroprotective effect of minocycline in experimentally induced gastric ulcers in rats.
Minocycline (MCN), a semi-synthetic tetracycline derivative possesses pleiotropic effects and provides protection against a number of disease models. However its effect on gastric ulcers has not been studied. The present investigation was undertaken, to study the gastro-protective potential of MCN in experimentally induced gastric ulcers in rats. MCN (10, 30, 100 mg/Kg) was tested for gastric s...
متن کاملAdipoRon may be benefit for atherosclerosis prevention
Atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. Adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. Disturbed adiponectin actions through its receptor, (AdipoR1 and AdipoR2) may be involved in atheros...
متن کاملGastroprotective effects of Thymus daenensis hydroalcoholic extract against ethanol-induced gastric mucosal ulcers in rats
Background & Aim: Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus daenensis has various components such as flavonoids which contribute to gastroprotection. Experimental: 35 <em...
متن کاملGastroprotective and ulcer healing effects of piptadeniastrum Africanum on experimentally induced gastric ulcers in rats
BACKGROUND Gastric peptic ulcer is one of the common disorders of gastrointestinal tract, which occur due to an imbalance between the offensive and defensive factors. It is an illness that affects a considerable number of people worldwide. This study was conducted to evaluate the antiulcerogenic and antiulcer effects and recognize the basic mechanism of action of Piptadeniastrum africanum stem ...
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ژورنال
عنوان ژورنال: Molecules
سال: 2021
ISSN: 1420-3049
DOI: 10.3390/molecules26102946